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Cisplatin-Membrane Interactions and Their Influence on Platinum Complexes Activity and Toxicity
Cisplatin and other platinum(II) analogs are widely used in clinical practice as anti-cancer drugs for a wide range of tumors. The primary mechanism by which they exert their action is through the formation of adducts with genomic DNA. However, multiple cellular targets by platinum(II) complexes hav...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336831/ https://www.ncbi.nlm.nih.gov/pubmed/30687116 http://dx.doi.org/10.3389/fphys.2018.01898 |