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Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia

The genetic architecture of schizophrenia (SCZ) includes numerous risk loci across a range of frequencies and sizes, including common and rare single-nucleotide variants and insertions/deletions (indels), as well as rare copy number variants (CNVs). Despite the clear heritability of the disease, mon...

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Detalles Bibliográficos
Autores principales: Fullard, John F., Charney, Alexander W., Voloudakis, Georgios, Uzilov, Andrew V., Haroutunian, Vahram, Roussos, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336839/
https://www.ncbi.nlm.nih.gov/pubmed/30655504
http://dx.doi.org/10.1038/s41398-018-0342-0