PD-1/PD-L1 Pathway Modulates Macrophage Susceptibility to Mycobacterium tuberculosis Specific CD8(+) T cell Induced Death

CD8(+)T cells contribute to tuberculosis (TB) infection control by inducing death of infected macrophages. Mycobacterium tuberculosis (Mtb) infection is associated with increased PD-1/PD-L1 expression and alternative activation of macrophages. We aimed to study the role of PD-1 pathway and macrophag...

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Detalles Bibliográficos
Autores principales: Suarez, Guadalupe Verónica, Melucci Ganzarain, Claudia del Carmen, Vecchione, María Belén, Trifone, César Ariel, Marín Franco, José Luis, Genoula, Melanie, Moraña, Eduardo José, Balboa, Luciana, Quiroga, Maria Florencia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336852/
https://www.ncbi.nlm.nih.gov/pubmed/30655556
http://dx.doi.org/10.1038/s41598-018-36403-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336852/
https://www.ncbi.nlm.nih.gov/pubmed/30655556
http://dx.doi.org/10.1038/s41598-018-36403-2

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