The circadian E3 ligase complex SCF(FBXL3+CRY) targets TLK2

We recently demonstrated that the circadian clock component CRY2 is an essential cofactor in the SCF(FBXL3)-mediated ubiquitination of c-MYC. Because our demonstration that CRY2 recruits phosphorylated substrates to SCF(FBXL3) was unexpected, we investigated the scope of this role by searching for a...

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Detalles Bibliográficos
Autores principales: Correia, Stephanie Papp, Chan, Alanna B., Vaughan, Megan, Zolboot, Norjin, Perea, Valerie, Huber, Anne-Laure, Kriebs, Anna, Moresco, James J., Yates, John R., Lamia, Katja A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336870/
https://www.ncbi.nlm.nih.gov/pubmed/30655559
http://dx.doi.org/10.1038/s41598-018-36618-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336870/
https://www.ncbi.nlm.nih.gov/pubmed/30655559
http://dx.doi.org/10.1038/s41598-018-36618-3

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