WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation

Stability regulation of RAS that can affect its activity, in addition to the oncogenic mutations, occurs in human cancer. However, the mechanisms for stability regulation of RAS involved in their activity and its roles in tumorigenesis are poorly explored. Here, we identify WD40-repeat protein 76 (W...

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Detalles Bibliográficos
Autores principales: Jeong, Woo-Jeong, Park, Jong-Chan, Kim, Woo-Shin, Ro, Eun Ji, Jeon, Soung Hoo, Lee, Sang-Kyu, Park, Young Nyun, Min, Do Sik, Choi, Kang-Yell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336889/
https://www.ncbi.nlm.nih.gov/pubmed/30655611
http://dx.doi.org/10.1038/s41467-018-08230-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336889/
https://www.ncbi.nlm.nih.gov/pubmed/30655611
http://dx.doi.org/10.1038/s41467-018-08230-6

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