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Computational Protocol to Understand P450 Mechanisms and Design of Efficient and Selective Biocatalysts
Cytochrome P450 enzymes have gained significant interest as selective oxidants in late-stage chemical synthesis. Their broad substrate scope enables them to be good candidates for their use in non-natural reactivity. Directed evolution evolves new enzyme biocatalysts that promote alternative reactiv...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336901/ https://www.ncbi.nlm.nih.gov/pubmed/30687699 http://dx.doi.org/10.3389/fchem.2018.00663 |