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Increased expression of brain-derived neurotrophic factor is correlated with visceral hypersensitivity in patients with diarrhea-predominant irritable bowel syndrome

BACKGROUND: Visceral hypersensitivity is considered to play a vital role in the pathogenesis of irritable bowel syndrome (IBS). Neurotrophins have drawn much attention in IBS recently. Brain-derived neurotrophic factor (BDNF) was found to mediate visceral hypersensitivity via facilitating sensory ne...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Qin, Geng, Liu, De-Rong, Wang, Yan, Yao, Shu-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337018/
https://www.ncbi.nlm.nih.gov/pubmed/30670915
http://dx.doi.org/10.3748/wjg.v25.i2.269