Thiophene Derivatives as Anticancer Agents and Their Delivery to Tumor Cells Using Albumin Nanoparticles

A series of thiophene derivatives (TPs) were synthesized and evaluated for cytotoxicity in HepG2 and SMMC-7721 cell lines by MTT assay. TP 5 was identified as a potential anticancer agent based on its ability to inhibit tumor cell growth. Drawbacks of TPs, including poor solubility and high toxicity...

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Detalles Bibliográficos
Autores principales: Cai, Guangsheng, Wang, Simiao, Zhao, Lang, Sun, Yating, Yang, Dongsheng, Lee, Robert J., Zhao, Menghui, Zhang, Huan, Zhou, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337126/
https://www.ncbi.nlm.nih.gov/pubmed/30621360
http://dx.doi.org/10.3390/molecules24010192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337126/
https://www.ncbi.nlm.nih.gov/pubmed/30621360
http://dx.doi.org/10.3390/molecules24010192

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