Periostin Mediates Right Ventricular Failure through Induction of Inducible Nitric Oxide Synthase Expression in Right Ventricular Fibroblasts from Monocrotaline-Induced Pulmonary Arterial Hypertensive Rats

Pulmonary arterial hypertension (PAH) leads to lethal right ventricular failure (RVF). Periostin (POSTN) mRNA expression is increased in right ventricles (RVs) of monocrotaline (MCT)-induced PAH model rats. However, the pathophysiological role of POSTN in RVF has not been clarified. We investigated...

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Detalles Bibliográficos
Autores principales: Imoto, Keisuke, Okada, Muneyoshi, Yamawaki, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337160/
https://www.ncbi.nlm.nih.gov/pubmed/30586863
http://dx.doi.org/10.3390/ijms20010062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337160/
https://www.ncbi.nlm.nih.gov/pubmed/30586863
http://dx.doi.org/10.3390/ijms20010062

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