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Ursolic Acid Induces Apoptosis in Colorectal Cancer Cells Partially via Upregulation of MicroRNA-4500 and Inhibition of JAK2/STAT3 Phosphorylation

Though ursolic acid (UA) isolated from Oldenlandia diffusa was known to exhibit anti-cancer, anti-inflammatory, and anti-obesity effects, the underlying antitumor mechanism of ursolic acid was not fully understood to date. Thus, in the present study, the apoptotic mechanism of ursolic acid was eluci...

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Detalles Bibliográficos
Autores principales: Kim, Karam, Shin, Eun Ah, Jung, Ji Hoon, Park, Ji Eon, Kim, Dong Soub, Shim, Bum Sang, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337206/
https://www.ncbi.nlm.nih.gov/pubmed/30597956
http://dx.doi.org/10.3390/ijms20010114