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Molecular Dynamics Simulations of Wild Type and Mutants of SAPAP in Complexed with Shank3

Specific interactions between scaffold protein SH3 and multiple ankyrin repeat domains protein 3 (Shank3) and synapse-associated protein 90/postsynaptic density-95–associated protein (SAPAP) are essential for excitatory synapse development and plasticity. In a bunch of human neurological diseases, m...

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Detalles Bibliográficos
Autores principales: Piao, Lianhua, Chen, Zhou, Li, Qiuye, Liu, Ranran, Song, Wei, Kong, Ren, Chang, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337207/
https://www.ncbi.nlm.nih.gov/pubmed/30626119
http://dx.doi.org/10.3390/ijms20010224