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R-Fluoxetine Increases Melanin Synthesis Through a 5-HT1A/2A Receptor and p38 MAPK Signaling Pathways

Fluoxetine, a member of the class of selective serotonin reuptake inhibitors, is a racemic mixture and has an anxiolytic effect in rodents. Previously, we have shown that fluoxetine can up-regulate melanin synthesis in B16F10 melanoma cells and normal human melanocytes (NMHM). However, the role of r...

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Detalles Bibliográficos
Autores principales: Liu, Li, Fu, Mengsi, Pei, Siran, Zhou, Liangliang, Shang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337216/
https://www.ncbi.nlm.nih.gov/pubmed/30585252
http://dx.doi.org/10.3390/ijms20010080