Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice

Sialic acid-binding Ig-like lectin 8 (Siglec-8) is expressed on the surface of human eosinophils, mast cells, and basophils—cells that participate in allergic and other diseases. Ligation of Siglec-8 by specific glycan ligands or antibodies triggers eosinophil death and inhibits mast cell degranulat...

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Detalles Bibliográficos
Autores principales: Wei, Yadong, Chhiba, Krishan D., Zhang, Fengrui, Ye, Xujun, Wang, Lihui, Zhang, Li, Robida, Piper A., Moreno-Vinasco, Liliana, Schnaar, Ronald L., Roers, Axel, Hartmann, Karin, Lee, Chang-Min, Demers, Delia, Zheng, Tao, Bochner, Bruce S., Zhu, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337227/
https://www.ncbi.nlm.nih.gov/pubmed/30577572
http://dx.doi.org/10.3390/ijms20010019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337227/
https://www.ncbi.nlm.nih.gov/pubmed/30577572
http://dx.doi.org/10.3390/ijms20010019

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