Cargando…

Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice

Sialic acid-binding Ig-like lectin 8 (Siglec-8) is expressed on the surface of human eosinophils, mast cells, and basophils—cells that participate in allergic and other diseases. Ligation of Siglec-8 by specific glycan ligands or antibodies triggers eosinophil death and inhibits mast cell degranulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Yadong, Chhiba, Krishan D., Zhang, Fengrui, Ye, Xujun, Wang, Lihui, Zhang, Li, Robida, Piper A., Moreno-Vinasco, Liliana, Schnaar, Ronald L., Roers, Axel, Hartmann, Karin, Lee, Chang-Min, Demers, Delia, Zheng, Tao, Bochner, Bruce S., Zhu, Zhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337227/ https://www.ncbi.nlm.nih.gov/pubmed/30577572 http://dx.doi.org/10.3390/ijms20010019

Ejemplares similares

Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells
por: Robida, Piper A., et al.
Publicado: (2022)

Potential Targeting of Siglecs, Mast Cell Inhibitory Receptors, in Interstitial Cystitis
por: Park, Chang-Shin, et al.
Publicado: (2011)

Siglec Ligands
por: Gonzalez-Gil, Anabel, et al.
Publicado: (2021)

Sialylated keratan sulfate proteoglycans are Siglec-8 ligands in human airways
por: Gonzalez-Gil, Anabel, et al.
Publicado: (2018)

Interactions between Siglec-8 and endogenous sialylated cis ligands restrain cell death induction in human eosinophils and mast cells
por: Cao, Yun, et al.
Publicado: (2023)

Mouse mast cells and mast cell proteases do not play a significant role in acute tissue injury pain induced by formalin
por: Magnúsdóttir, Elín I, et al.
Publicado: (2018)

Mast cells promote melanoma colonization of lungs
por: Öhrvik, Helena, et al.
Publicado: (2016)

Mast cell-specific Cre/loxP-mediated recombination in vivo
por: Scholten, Julia, et al.
Publicado: (2007)

Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody
por: Gebremeskel, Simon, et al.
Publicado: (2021)

Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells
por: Schanin, Julia, et al.
Publicado: (2022)

Allergic inflammation is initiated by IL-33–dependent crosstalk between mast cells and basophils
por: Hsu, Chia-Lin, et al.
Publicado: (2020)

Glycobiology of Eosinophilic Inflammation: Contributions of Siglecs, Glycans, and Other Glycan-Binding Proteins
por: O’Sullivan, Jeremy A., et al.
Publicado: (2017)

Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells
por: Yu, Yingxin, et al.
Publicado: (2018)

Discovery, Function, and Therapeutic Targeting of Siglec-8
por: Youngblood, Bradford A., et al.
Publicado: (2020)

The mast cell/S1P axis is not linked to pre-lesional male skin remodeling in a mouse model of eczema
por: Tanis, Ross M., et al.
Publicado: (2021)

Skin Mast Cell-Driven Ceramides Drive Early Apoptosis in Pre-Symptomatic Eczema in Mice
por: Robida, Piper A., et al.
Publicado: (2021)

No Role for Mast Cells in Obesity-Related Metabolic Dysregulation
por: Chmelař, Jindřich, et al.
Publicado: (2016)

Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro
por: Carroll, Daniela J., et al.
Publicado: (2021)

New Insights into the Mechanism of the Down-Regulation of Mast Cells in the Treatment of Interstitial Cystitis: Possible Role of Siglecs
por: Lee, Tack
Publicado: (2011)

Identification of a Siglec-F+ granulocyte-macrophage progenitor
por: Bolden, Jessica E., et al.
Publicado: (2018)

Molecular cloning of porcine Siglec-3, Siglec-5 and Siglec-10, and identification of Siglec-10 as an alternative receptor for porcine reproductive and respiratory syndrome virus (PRRSV)
por: Xie, Jiexiong, et al.
Publicado: (2017)

Selective ablation of mast cells or basophils in mice reduces peanut-induced anaphylaxis
por: Reber, LL, et al.
Publicado: (2013)

Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates
por: Hayakawa, Toshiyuki, et al.
Publicado: (2017)

Selective deletion of SHIP-1 in hematopoietic cells in mice leads to severe lung inflammation involving ILC2 cells
por: Ye, Xujun, et al.
Publicado: (2021)

Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer’s disease
por: Gonzalez-Gil, Anabel, et al.
Publicado: (2022)

The Roles of Siglec7 and Siglec9 on Natural Killer Cells in Virus Infection and Tumour Progression
por: Zheng, Yayun, et al.
Publicado: (2020)

Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9
por: Rodriguez, Ernesto, et al.
Publicado: (2021)

Heparin is required for the formation of granules in connective tissue mast cells
por: Herrera-Heredia, Sandra Abril, et al.
Publicado: (2022)

Mechanisms of Siglec-F-Induced Eosinophil Apoptosis: A Role for Caspases but Not for SHP-1, Src Kinases, NADPH Oxidase or Reactive Oxygen
por: Mao, Hui, et al.
Publicado: (2013)

Siglecs at the Host–Pathogen Interface
por: Chang, Yung-Chi, et al.
Publicado: (2020)

Siglecs as Therapeutic Targets in Cancer
por: Lim, Jackwee, et al.
Publicado: (2021)

Siglec Signaling in the Tumor Microenvironment
por: van Houtum, Eline J. H., et al.
Publicado: (2021)

A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation
por: Schanin, Julia, et al.
Publicado: (2020)

The Inhibitory Receptor Siglec-8 Interacts With FcεRI and Globally Inhibits Intracellular Signaling in Primary Mast Cells Upon Activation
por: Korver, Wouter, et al.
Publicado: (2022)

Resveratrol Protects against Skin Inflammation through Inhibition of Mast Cell, Sphingosine Kinase-1, Stat3 and NF-κB p65 Signaling Activation in Mice
por: Carlucci, Christopher D., et al.
Publicado: (2023)

Siglecs in Brain Function and Neurological Disorders
por: Siddiqui, Shoib Sarwar, et al.
Publicado: (2019)

Development of an Immunohistochemical Assay for Siglec-15
por: Shafi, Saba, et al.
Publicado: (2022)

Common determinants of severe Covid-19 infection are explicable by SARS-CoV-2 secreted glycoprotein interaction with the CD33-related Siglecs, Siglec-3 and Siglec-5/14
por: Murch, Simon H.
Publicado: (2020)

A20-Deficient Mast Cells Exacerbate Inflammatory Responses In Vivo
por: Heger, Klaus, et al.
Publicado: (2014)

The Role of Mast Cells in Autoimmune Bullous Dermatoses
por: Yu, Xinhua, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3neag3gjfsfsga99vt7r7vmeud