Toward of Safer Phenylbutazone Derivatives by Exploration of Toxicity Mechanism

A drug design for safer phenylbutazone was been explored by reactivity and docking studies involving single electron transfer mechanism, as well as toxicological predictions. Several approaches about its structural properties were performed through quantum chemistry calculations at the B3LYP level o...

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Detalles Bibliográficos
Autores principales: Borges, Rosivaldo S., Palheta, Ivanete C., Ota, Sirlene S. B., Morais, Roberto B., Barros, Valéria A., Ramos, Ryan S., Silva, Rai C., Costa, Josivan da S., Silva, Carlos H. T. P., Campos, Joaquín M., Santos, Cleydson B. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337259/
https://www.ncbi.nlm.nih.gov/pubmed/30609687
http://dx.doi.org/10.3390/molecules24010143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337259/
https://www.ncbi.nlm.nih.gov/pubmed/30609687
http://dx.doi.org/10.3390/molecules24010143

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