Site-directed Mutagenesis of a β-Glycoside Hydrolase from Lentinula edodes

The β-glycoside hydrolases (LXYL-P1−1 and LXYL-P1−2) from Lentinula edodes (strain M95.33) can specifically hydrolyze 7-β-xylosyl-10-deacetyltaxol (XDT) to form 10-deacetyltaxol for the semi-synthesis of Taxol. Our previous study showed that both the I368T mutation in LXYL-P1−1 and the T368E mutatio...

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Detalles Bibliográficos
Autores principales: Chen, Jing-Jing, Liang, Xiao, Chen, Tian-Jiao, Yang, Jin-Ling, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337304/
https://www.ncbi.nlm.nih.gov/pubmed/30586935
http://dx.doi.org/10.3390/molecules24010059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337304/
https://www.ncbi.nlm.nih.gov/pubmed/30586935
http://dx.doi.org/10.3390/molecules24010059

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