The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

Alzheimer’s disease (AD) is the leading cause of dementia worldwide. The extracellular deposits of Amyloid beta (Aβ) in the brain—called amyloid plaques, and neurofibrillary tangles—intracellular tau aggregates, are morphological hallmarks of the disease. The risk for AD is a complicated interplay b...

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Detalles Bibliográficos
Autores principales: Wolfe, Cody M., Fitz, Nicholas F., Nam, Kyong Nyon, Lefterov, Iliya, Koldamova, Radosveta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337314/
https://www.ncbi.nlm.nih.gov/pubmed/30587772
http://dx.doi.org/10.3390/ijms20010081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337314/
https://www.ncbi.nlm.nih.gov/pubmed/30587772
http://dx.doi.org/10.3390/ijms20010081

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