Detection of Low-Frequency Mutations and Identification of Heat-Induced Artifactual Mutations Using Duplex Sequencing

We present a genome-wide comparative and comprehensive analysis of three different sequencing methods (conventional next generation sequencing (NGS), tag-based single strand sequencing (e.g., SSCS), and Duplex Sequencing for investigating mitochondrial mutations in human breast epithelial cells. Dup...

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Detalles Bibliográficos
Autores principales: Ahn, Eun Hyun, Lee, Seung Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337315/
https://www.ncbi.nlm.nih.gov/pubmed/30625989
http://dx.doi.org/10.3390/ijms20010199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337315/
https://www.ncbi.nlm.nih.gov/pubmed/30625989
http://dx.doi.org/10.3390/ijms20010199

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