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Essential Role of Endothelial MCPIP in Vascular Integrity and Post-Ischemic Remodeling

MCP-1-induced protein (MCPIP, also known as Zc3h12a or Regnase-1), a newly identified suppressor of cytokine signaling, is expressed in endothelial cells (ECs). To investigate the role of endothelial MCPIP in vascular homeostasis and function, we deleted the MCPIP gene specifically in ECs using the...

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Detalles Bibliográficos
Autores principales: Jin, Zhuqing, Niu, Jianli, Kapoor, Nidhi, Liang, Jian, Becerra, Edilu, Kolattukudy, Pappachan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337340/
https://www.ncbi.nlm.nih.gov/pubmed/30621250
http://dx.doi.org/10.3390/ijms20010172