Identifying Protein Features Responsible for Improved Drug Repurposing Accuracies Using the CANDO Platform: Implications for Drug Design

Drug repurposing is a valuable tool for combating the slowing rates of novel therapeutic discovery. The Computational Analysis of Novel Drug Opportunities (CANDO) platform performs shotgun repurposing of 2030 indications/diseases using 3733 drugs/compounds to predict interactions with 46,784 protein...

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Detalles Bibliográficos
Autores principales: Mangione, William, Samudrala, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337359/
https://www.ncbi.nlm.nih.gov/pubmed/30621144
http://dx.doi.org/10.3390/molecules24010167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337359/
https://www.ncbi.nlm.nih.gov/pubmed/30621144
http://dx.doi.org/10.3390/molecules24010167

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