Morniga-G, a T/Tn-Specific Lectin, Induces Leukemic Cell Death via Caspase and DR5 Receptor-Dependent Pathways

Morniga-G, the Gal-specific black mulberry (Morus nigra) lectin, displays high affinity for T (CD176) and Tn (CD175) antigens, frequently expressed at the cancer cell surface. The effects of Morniga-G were investigated on a Tn-positive leukemic Jurkat cell line. The lectin, used in a concentration r...

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Detalles Bibliográficos
Autores principales: Poiroux, Guillaume, Barre, Annick, Simplicien, Mathias, Pelofy, Sandrine, Ségui, Bruno, Van Damme, Els J. M., Rougé, Pierre, Benoist, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337360/
https://www.ncbi.nlm.nih.gov/pubmed/30626136
http://dx.doi.org/10.3390/ijms20010230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337360/
https://www.ncbi.nlm.nih.gov/pubmed/30626136
http://dx.doi.org/10.3390/ijms20010230

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