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Pro-Inflammatory Stimuli Influence Expression of Intercellular Adhesion Molecule 1 in Human Anulus Fibrosus Cells through FAK/ERK/GSK3 and PKCδ Signaling Pathways

Objective: Intervertebral disc (IVD) degeneration and disc herniation are major causes of lower back pain, which involve the presence of inflammatory mediators and tissue invasion by immune cells. Intercellular adhesion molecule 1 (ICAM1, also termed CD54) is an adhesion molecule that mediates cell-...

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Detalles Bibliográficos
Autores principales: Huang, Bor-Ren, Bau, Da-Tian, Chen, Tzu-Sheng, Chuang, I-Chen, Tsai, Cheng-Fang, Chang, Pei-Chun, Hsu, Horng-Chaung, Lu, Dah-Yuu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337379/
https://www.ncbi.nlm.nih.gov/pubmed/30585203
http://dx.doi.org/10.3390/ijms20010077