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Pro-Inflammatory Stimuli Influence Expression of Intercellular Adhesion Molecule 1 in Human Anulus Fibrosus Cells through FAK/ERK/GSK3 and PKCδ Signaling Pathways
Objective: Intervertebral disc (IVD) degeneration and disc herniation are major causes of lower back pain, which involve the presence of inflammatory mediators and tissue invasion by immune cells. Intercellular adhesion molecule 1 (ICAM1, also termed CD54) is an adhesion molecule that mediates cell-...
Autores principales: | Huang, Bor-Ren, Bau, Da-Tian, Chen, Tzu-Sheng, Chuang, I-Chen, Tsai, Cheng-Fang, Chang, Pei-Chun, Hsu, Horng-Chaung, Lu, Dah-Yuu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337379/ https://www.ncbi.nlm.nih.gov/pubmed/30585203 http://dx.doi.org/10.3390/ijms20010077 |
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