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In-Cell NMR Study of Tau and MARK2 Phosphorylated Tau

The intrinsically disordered protein, Tau, is abundant in neurons and contributes to the regulation of the microtubule (MT) and actin network, while its intracellular abnormal aggregation is closely associated with Alzheimer’s disease. Here, using in-cell Nuclear Magnetic Resonance (NMR) spectroscop...

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Detalles Bibliográficos
Autores principales: Zhang, Shengnan, Wang, Chuchu, Lu, Jinxia, Ma, Xiaojuan, Liu, Zhenying, Li, Dan, Liu, Zhijun, Liu, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337406/
https://www.ncbi.nlm.nih.gov/pubmed/30587819
http://dx.doi.org/10.3390/ijms20010090