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Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer

Human exonuclease 1 (EXO1), a 5′→3′ exonuclease, contributes to the regulation of the cell cycle checkpoints, replication fork maintenance, and post replicative DNA repair pathways. These processes are required for the resolution of stalled or blocked DNA replication that can lead to replication str...

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Detalles Bibliográficos
Autores principales: Keijzers, Guido, Bakula, Daniela, Petr, Michael Angelo, Madsen, Nils Gedsig Kirkelund, Teklu, Amanuel, Mkrtchyan, Garik, Osborne, Brenna, Scheibye-Knudsen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337416/
https://www.ncbi.nlm.nih.gov/pubmed/30585186
http://dx.doi.org/10.3390/ijms20010074