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Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction

Soybeans display strategic potential in food security as a source of protein and functional bioactives for human consumption. Polyphenols and other bioactive compounds can be recovered after an aqueous extraction from soybean meal, a byproduct of soy oil refining. The objective of the present study...

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Autores principales: S. Freitas, Cyntia, Alves da Silva, Genilton, Perrone, Daniel, A. Vericimo, Mauricio, dos S. Baião, Diego, R. Pereira, Patrícia, M. F. Paschoalin, Vânia, M. Del Aguila, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337456/
https://www.ncbi.nlm.nih.gov/pubmed/30587803
http://dx.doi.org/10.3390/molecules24010074
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author S. Freitas, Cyntia
Alves da Silva, Genilton
Perrone, Daniel
A. Vericimo, Mauricio
dos S. Baião, Diego
R. Pereira, Patrícia
M. F. Paschoalin, Vânia
M. Del Aguila, Eduardo
author_facet S. Freitas, Cyntia
Alves da Silva, Genilton
Perrone, Daniel
A. Vericimo, Mauricio
dos S. Baião, Diego
R. Pereira, Patrícia
M. F. Paschoalin, Vânia
M. Del Aguila, Eduardo
author_sort S. Freitas, Cyntia
collection PubMed
description Soybeans display strategic potential in food security as a source of protein and functional bioactives for human consumption. Polyphenols and other bioactive compounds can be recovered after an aqueous extraction from soybean meal, a byproduct of soy oil refining. The objective of the present study was to compile and quantify compounds from soybean oil refinery by-products, providing information about valuable bioactive phytochemicals, their bioaccessibility and potential bioactivities. Genistin, daidzin, glycitin and malonylgenistin were the predominant isoflavones, and the overall bioaccessibility of their glycosidic forms was of nearly 75%. Sixteen phenolics were identified and caffeic acid, 5-caffeoylquinic chlorogenic acid and hesperidin were the most predominant. Approximately 30% of gallic acid, syringic acid, vanillic acid and myricetin were released and the antioxidant capacity of aqueous extract was enhanced after simulated in vitro gastro intestinal digestion. The ability of aqueous soybean meal extract to inhibit lipid peroxidation was higher than natural and synthetic food antioxidants. Antimicrobial activity against several foodborne pathogens and antitumoral activity towards human glioblastoma cell line were also observed, but the aqueous extract showed no cytotoxicity to healthy murine cells. Compounds derived from the aqueous soybean meal extract have the potential to be used as health promoting agents.
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spelling pubmed-63374562019-01-25 Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction S. Freitas, Cyntia Alves da Silva, Genilton Perrone, Daniel A. Vericimo, Mauricio dos S. Baião, Diego R. Pereira, Patrícia M. F. Paschoalin, Vânia M. Del Aguila, Eduardo Molecules Article Soybeans display strategic potential in food security as a source of protein and functional bioactives for human consumption. Polyphenols and other bioactive compounds can be recovered after an aqueous extraction from soybean meal, a byproduct of soy oil refining. The objective of the present study was to compile and quantify compounds from soybean oil refinery by-products, providing information about valuable bioactive phytochemicals, their bioaccessibility and potential bioactivities. Genistin, daidzin, glycitin and malonylgenistin were the predominant isoflavones, and the overall bioaccessibility of their glycosidic forms was of nearly 75%. Sixteen phenolics were identified and caffeic acid, 5-caffeoylquinic chlorogenic acid and hesperidin were the most predominant. Approximately 30% of gallic acid, syringic acid, vanillic acid and myricetin were released and the antioxidant capacity of aqueous extract was enhanced after simulated in vitro gastro intestinal digestion. The ability of aqueous soybean meal extract to inhibit lipid peroxidation was higher than natural and synthetic food antioxidants. Antimicrobial activity against several foodborne pathogens and antitumoral activity towards human glioblastoma cell line were also observed, but the aqueous extract showed no cytotoxicity to healthy murine cells. Compounds derived from the aqueous soybean meal extract have the potential to be used as health promoting agents. MDPI 2018-12-26 /pmc/articles/PMC6337456/ /pubmed/30587803 http://dx.doi.org/10.3390/molecules24010074 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
S. Freitas, Cyntia
Alves da Silva, Genilton
Perrone, Daniel
A. Vericimo, Mauricio
dos S. Baião, Diego
R. Pereira, Patrícia
M. F. Paschoalin, Vânia
M. Del Aguila, Eduardo
Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_full Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_fullStr Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_full_unstemmed Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_short Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_sort recovery of antimicrobials and bioaccessible isoflavones and phenolics from soybean (glycine max) meal by aqueous extraction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337456/
https://www.ncbi.nlm.nih.gov/pubmed/30587803
http://dx.doi.org/10.3390/molecules24010074
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