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The Synergistic Effects of APOE Genotype and Obesity on Alzheimer’s Disease Risk
The APOE gene has three common alleles—E2, E3, and E4, with APOE4 being the strongest genetic risk factor for developing Alzheimer’s Disease (AD). Obesity is a global epidemic and contributes to multiple metabolic problems. Obesity is also a risk factor for cognitive decline. Here, we review the eff...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337558/ https://www.ncbi.nlm.nih.gov/pubmed/30586872 http://dx.doi.org/10.3390/ijms20010063 |