Binding of Small Molecules to G-quadruplex DNA in Cells Revealed by Fluorescence Lifetime Imaging Microscopy of o-BMVC Foci

G-quadruplex (G4) structures have recently received increasing attention as a potential target for cancer research. We used time-gated fluorescence lifetime imaging microscopy (FLIM) with a G4 fluorescent probe, 3,6-bis(1-methyl-2-vinylpyridinium) carbazole diiodide (o-BMVC), to measure the number o...

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Detalles Bibliográficos
Autores principales: Tseng, Ting-Yuan, Chu, I-Te, Lin, Shang-Jyun, Li, Jie, Chang, Ta-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337594/
https://www.ncbi.nlm.nih.gov/pubmed/30583464
http://dx.doi.org/10.3390/molecules24010035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337594/
https://www.ncbi.nlm.nih.gov/pubmed/30583464
http://dx.doi.org/10.3390/molecules24010035

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