Cargando…

Binding of Small Molecules to G-quadruplex DNA in Cells Revealed by Fluorescence Lifetime Imaging Microscopy of o-BMVC Foci

G-quadruplex (G4) structures have recently received increasing attention as a potential target for cancer research. We used time-gated fluorescence lifetime imaging microscopy (FLIM) with a G4 fluorescent probe, 3,6-bis(1-methyl-2-vinylpyridinium) carbazole diiodide (o-BMVC), to measure the number o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tseng, Ting-Yuan, Chu, I-Te, Lin, Shang-Jyun, Li, Jie, Chang, Ta-Chau
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337594/ https://www.ncbi.nlm.nih.gov/pubmed/30583464 http://dx.doi.org/10.3390/molecules24010035

Ejemplares similares

Antisense Oligonucleotides Used to Identify Telomeric G-Quadruplexes in Metaphase Chromosomes and Fixed Cells by Fluorescence Lifetime Imaging Microscopy of o-BMVC Foci
por: Tseng, Ting-Yuan, et al.
Publicado: (2020)

Folding and Unfolding of Exogenous G-Rich Oligonucleotides in Live Cells by Fluorescence Lifetime Imaging Microscopy of o-BMVC Fluorescent Probe
por: Tseng, Ting-Yuan, et al.
Publicado: (2021)

Emulsified BMVC derivative induced filtration for G-quadruplex DNA structural separation
por: Tsai, Yu-Lin, et al.
Publicado: (2011)

Custom G4 Microarrays Reveal Selective G-Quadruplex Recognition of Small Molecule BMVC: A Large-Scale Assessment of Ligand Binding Selectivity
por: Wu, Guanhui, et al.
Publicado: (2020)

Pilot imaging study of o-BMVC foci for discrimination of indeterminate cytology in diagnosing fine-needle aspiration of thyroid nodules
por: Tseng, Ting-Yuan, et al.
Publicado: (2021)

Investigation of spectral conversion of d(TTAGGG)(4) and d(TTAGGG)(13) upon potassium titration by a G-quadruplex recognizer BMVC molecule
por: Chang, Cheng-Chung, et al.
Publicado: (2007)

Structural Change from Nonparallel to Parallel G-Quadruplex Structures in Live Cancer Cells Detected in the Lysosomes Using Fluorescence Lifetime Imaging Microscopy
por: Tseng, Ting-Yuan, et al.
Publicado: (2022)

The interactions between a small molecule and G-quadruplexes are visualized by fluorescence lifetime imaging microscopy
por: Shivalingam, Arun, et al.
Publicado: (2015)

Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition
por: Liu, Wenting, et al.
Publicado: (2019)

BMVC test, an improved fluorescence assay for detection of malignant pleural effusions
por: Lin, I-Ting, et al.
Publicado: (2014)

Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy
por: Summers, Peter A., et al.
Publicado: (2021)

Modulating the G‐Quadruplex and Duplex DNA Binding by Controlling the Charge of Fluorescent Molecules
por: Gil‐Martínez, Ariadna, et al.
Publicado: (2022)

The G-quadruplex fluorescent probe 3,6-bis(1-methyl-2-vinyl-pyridinium) carbazole diiodide as a biosensor for human cancers
por: Tseng, Ting-Yuan, et al.
Publicado: (2018)

Advanced Data Analysis for Fluorescence-Lifetime Single-Molecule Localization Microscopy
por: Thiele, Jan Christoph, et al.
Publicado: (2021)

Detection of Cell Carcinogenic Transformation by a Quadruplex DNA Binding Fluorescent Probe
por: Yang, Tsung-Lin, et al.
Publicado: (2014)

Direct evidence of mitochondrial G-quadruplex DNA by using fluorescent anti-cancer agents
por: Huang, Wei-Chun, et al.
Publicado: (2015)

Binding Study of the Fluorescent Carbazole Derivative with Human Telomeric G-Quadruplexes
por: Głuszyńska, Agata, et al.
Publicado: (2018)

In-cell optical imaging of exogenous G-quadruplex DNA by fluorogenic ligands
por: Tseng, Ting-Yuan, et al.
Publicado: (2013)

Effects of Length and Loop Composition on Structural Diversity and Similarity of (G(3)TG(3)N(m)G(3)TG(3)) G-Quadruplexes
por: Li, Jie, et al.
Publicado: (2020)

Small Molecule Fluorescent Probes for G- Quadruplex Visualization as Potential Cancer Theranostic Agents
por: Chilka, Pallavi, et al.
Publicado: (2019)

Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA
por: Dickerhoff, Jonathan, et al.
Publicado: (2021)

Structured Waters Mediate Small Molecule Binding to G-Quadruplex Nucleic Acids
por: Neidle, Stephen
Publicado: (2021)

A G-Quadruplex Structure in the Promoter Region of CLIC4 Functions as a Regulatory Element for Gene Expression
por: Huang, Mu-Ching, et al.
Publicado: (2018)

A single molecule study of a fluorescently labeled telomestatin derivative and G-quadruplex interactions
por: Maleki, Parastoo, et al.
Publicado: (2017)

Evaluation of the selectivity of G-quadruplex ligands in living cells with a small molecule fluorescent probe
por: Zhang, Suge, et al.
Publicado: (2019)

Single-molecule fluorescence studies on cotranscriptional G-quadruplex formation coupled with R-loop formation
por: Lim, Gunhyoung, et al.
Publicado: (2020)

Metabolic fingerprinting of bacteria by fluorescence lifetime imaging microscopy
por: Bhattacharjee, Arunima, et al.
Publicado: (2017)

Light-field tomographic fluorescence lifetime imaging microscopy
por: Ma, Yayao, et al.
Publicado: (2023)

A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes
por: Wang, Zi-Fu, et al.
Publicado: (2016)

Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule
por: Welsh, Sarah J., et al.
Publicado: (2013)

Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex**
por: Yangyuoru, Philip M, et al.
Publicado: (2015)

Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex**
por: Yangyuoru, Philip M, et al.
Publicado: (2015)

Using Macrocyclic G‐Quadruplex Ligands to Decipher the Interactions Between Small Molecules and G‐Quadruplex DNA
por: Andréasson, Måns, et al.
Publicado: (2022)

Molecular engineering of G-quadruplex ligands based on solvent effect of polyethylene glycol
por: Wang, Zi-Fu, et al.
Publicado: (2012)

Real-time monitoring of DNA G-quadruplexes in living cells with a small-molecule fluorescent probe
por: Zhang, Suge, et al.
Publicado: (2018)

Single molecule microscopy reveals key physical features of repair foci in living cells
por: Miné-Hattab, Judith, et al.
Publicado: (2021)

Searching for G-Quadruplex-Binding Proteins in Plants: New Insight into Possible G-Quadruplex Regulation
por: Volná, Adriana, et al.
Publicado: (2021)

Multiphoton Laser Microscopy and Fluorescence Lifetime Imaging for the Evaluation of the Skin
por: Seidenari, Stefania, et al.
Publicado: (2012)

Simultaneous Fluorescence and Phosphorescence Lifetime Imaging Microscopy in Living Cells
por: Jahn, Karolina, et al.
Publicado: (2015)

Visualizing Intracellular SNARE Trafficking by Fluorescence Lifetime Imaging Microscopy
por: Verboogen, Daniëlle R. J., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_anfdcmcgtfrd4r1k0bta8tarmo