Cargando…

Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing

Sustained pacemaker function is a challenge in biological pacemaker engineering. Human cardiomyocyte progenitor cells (CMPCs) have exhibited extended survival in the heart after transplantation. We studied whether lentivirally transduced CMPCs that express the pacemaker current I(f) (encoded by HCN4...

Descripción completa

Detalles Bibliográficos
Autores principales: Végh, Anna M. D., den Haan, A. Dénise, Cócera Ortega, Lucía, Verkerk, Arie O., Sluijter, Joost P. G., Bakker, Diane, van Amersfoorth, Shirley, van Veen, Toon A. B., Klerk, Mischa, Seppen, Jurgen, de Bakker, Jacques M. T., Christoffels, Vincent M., Geerts, Dirk, Goumans, Marie José T. H., Tan, Hanno L., Boink, Gerard J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337610/
https://www.ncbi.nlm.nih.gov/pubmed/30621310
http://dx.doi.org/10.3390/molecules24010181