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Lignans from Bursera fagaroides Affect In Vivo Cell Behavior by Disturbing the Tubulin Cytoskeleton in Zebrafish Embryos

By using a zebrafish embryo model to guide the chromatographic fractionation of antimitotic secondary metabolites, seven podophyllotoxin-type lignans were isolated from a hydroalcoholic extract obtained from the steam bark of Bursera fagaroides. The compounds were identified as podophyllotoxin (1),...

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Detalles Bibliográficos
Autores principales: Antúnez-Mojica, Mayra, Rojas-Sepúlveda, Andrés M., Mendieta-Serrano, Mario A., Gonzalez-Maya, Leticia, Marquina, Silvia, Salas-Vidal, Enrique, Alvarez, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337621/
https://www.ncbi.nlm.nih.gov/pubmed/30577489
http://dx.doi.org/10.3390/molecules24010008