Design and Synthesis of C-19 Isosteviol Derivatives as Potent and Highly Selective Antiproliferative Agents

Six series of novel isosteviol derivatives; modified in the C-19 position; were synthesized; and their antiproliferative activity was evaluated against three human cancer cell lines (HCT-116; BEL-7402; HepG2) and the human L02 normal cell line in vitro. Most of the derivatives tested here exhibited...

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Detalles Bibliográficos
Autores principales: Luan, Tian, Cao, Li-Hua, Deng, Hao, Shen, Qing-Kun, Tian, Yu-Shun, Quan, Zhe-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337650/
https://www.ncbi.nlm.nih.gov/pubmed/30598028
http://dx.doi.org/10.3390/molecules24010121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337650/
https://www.ncbi.nlm.nih.gov/pubmed/30598028
http://dx.doi.org/10.3390/molecules24010121

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