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Aflatoxin B(1)–Formamidopyrimidine DNA Adducts: Relationships between Structures, Free Energies, and Melting Temperatures

Thermal stabilities of DNA duplexes containing Gua (g), α- (a) or β-anomer of formamidopyrimidine-N7-9-hydroxy-aflatoxin B(1) (b) differ markedly (T(m): [Formula: see text]), but the underlying molecular origin of this experimentally observed phenomenon is yet to be identified and determined. Here,...

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Detalles Bibliográficos
Autores principales: Klvana, Martin, Bren, Urban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337653/
https://www.ncbi.nlm.nih.gov/pubmed/30609733
http://dx.doi.org/10.3390/molecules24010150