Cargando…

LT-IIc, A Bacterial Type II Heat-Labile Enterotoxin, Induces Specific Lethality in Triple Negative Breast Cancer Cells by Modulation of Autophagy and Induction of Apoptosis and Necroptosis

Triple negative breast cancer (TNBC) remains a serious health problem with poor prognosis and limited therapeutic options. To discover novel approaches to treat TNBC, we screened cholera toxin (CT) and the members of the bacterial type II heat-labile enterotoxin family (LT-IIa, LT-IIb, and LT-IIc) f...

Descripción completa

Detalles Bibliográficos
Autores principales: Masso-Welch, Patricia, Girald Berlingeri, Sofia, King-Lyons, Natalie D., Mandell, Lorrie, Hu, John, Greene, Christopher J., Federowicz, Matthew, Cao, Peter, Connell, Terry D., Heakal, Yasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337683/
https://www.ncbi.nlm.nih.gov/pubmed/30587795
http://dx.doi.org/10.3390/ijms20010085