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LT-IIc, A Bacterial Type II Heat-Labile Enterotoxin, Induces Specific Lethality in Triple Negative Breast Cancer Cells by Modulation of Autophagy and Induction of Apoptosis and Necroptosis
Triple negative breast cancer (TNBC) remains a serious health problem with poor prognosis and limited therapeutic options. To discover novel approaches to treat TNBC, we screened cholera toxin (CT) and the members of the bacterial type II heat-labile enterotoxin family (LT-IIa, LT-IIb, and LT-IIc) f...
Autores principales: | Masso-Welch, Patricia, Girald Berlingeri, Sofia, King-Lyons, Natalie D., Mandell, Lorrie, Hu, John, Greene, Christopher J., Federowicz, Matthew, Cao, Peter, Connell, Terry D., Heakal, Yasser |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337683/ https://www.ncbi.nlm.nih.gov/pubmed/30587795 http://dx.doi.org/10.3390/ijms20010085 |
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