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Bypassing Glutamic Acid Decarboxylase 1 (Gad1) Induced Craniofacial Defects with a Photoactivatable Translation Blocker Morpholino

[Image: see text] γ-Amino butyric acid (GABA) mediated signaling is critical in the central and enteric nervous systems, pancreas, lungs, and other tissues. It is associated with many neurological disorders and craniofacial development. Glutamic acid decarboxylase (GAD) synthesizes GABA from glutama...

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Detalles Bibliográficos
Autores principales: O’Connor, Matthew J., Beebe, Lindsey L., Deodato, Davide, Ball, Rebecca E., Page, A. Tyler, VanLeuven, Ariel J., Harris, Kyle T., Park, Sungdae, Hariharan, Vani, Lauderdale, James D., Dore, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337688/
https://www.ncbi.nlm.nih.gov/pubmed/30200754
http://dx.doi.org/10.1021/acschemneuro.8b00231