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A junction coverage compatibility score to quantify the reliability of transcript abundance estimates and annotation catalogs

Most methods for statistical analysis of RNA-seq data take a matrix of abundance estimates for some type of genomic features as their input, and consequently the quality of any obtained results is directly dependent on the quality of these abundances. Here, we present the junction coverage compatibi...

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Detalles Bibliográficos
Autores principales: Soneson, Charlotte, Love, Michael I, Patro, Rob, Hussain, Shobbir, Malhotra, Dheeraj, Robinson, Mark D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337739/
https://www.ncbi.nlm.nih.gov/pubmed/30655364
http://dx.doi.org/10.26508/lsa.201800175