PPARα Agonist Suppresses Inflammation after Corneal Alkali Burn by Suppressing Proinflammatory Cytokines, MCP-1, and Nuclear Translocation of NF-κB

We investigated the effect of a peroxisome proliferator-activated receptor α (PPARα) agonist after corneal alkali injury. Fenofibrate 0.05% (PPARα agonist group) or vehicle (Vehicle group) was topically instilled onto the rat cornea after injury. Histological, immunohistochemical, and real-time reve...

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Detalles Bibliográficos
Autores principales: Nakano, Yuichiro, Uchiyama, Masaaki, Arima, Takeshi, Nagasaka, Shinya, Igarashi, Tsutomu, Shimizu, Akira, Takahashi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337747/
https://www.ncbi.nlm.nih.gov/pubmed/30597991
http://dx.doi.org/10.3390/molecules24010114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337747/
https://www.ncbi.nlm.nih.gov/pubmed/30597991
http://dx.doi.org/10.3390/molecules24010114

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