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PPARα Agonist Suppresses Inflammation after Corneal Alkali Burn by Suppressing Proinflammatory Cytokines, MCP-1, and Nuclear Translocation of NF-κB
We investigated the effect of a peroxisome proliferator-activated receptor α (PPARα) agonist after corneal alkali injury. Fenofibrate 0.05% (PPARα agonist group) or vehicle (Vehicle group) was topically instilled onto the rat cornea after injury. Histological, immunohistochemical, and real-time reve...
Autores principales: | Nakano, Yuichiro, Uchiyama, Masaaki, Arima, Takeshi, Nagasaka, Shinya, Igarashi, Tsutomu, Shimizu, Akira, Takahashi, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337747/ https://www.ncbi.nlm.nih.gov/pubmed/30597991 http://dx.doi.org/10.3390/molecules24010114 |
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