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APIM-Mediated REV3L–PCNA Interaction Important for Error Free TLS Over UV-Induced DNA Lesions in Human Cells

Proliferating cell nuclear antigen (PCNA) is essential for the organization of DNA replication and the bypass of DNA lesions via translesion synthesis (TLS). TLS is mediated by specialized DNA polymerases, which all interact, directly or indirectly, with PCNA. How interactions between the TLS polyme...

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Detalles Bibliográficos
Autores principales: Ræder, Synnøve Brandt, Nepal, Anala, Bjørås, Karine Øian, Seelinger, Mareike, Kolve, Rønnaug Steen, Nedal, Aina, Müller, Rebekka, Otterlei, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337749/
https://www.ncbi.nlm.nih.gov/pubmed/30597836
http://dx.doi.org/10.3390/ijms20010100