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Fascin-1 enhances experimental osteosarcoma tumor formation and metastasis and is related to poor patient outcome
BACKGROUND: Fascin-1, a prominent actin-bundling protein, is found to be upregulated in several human carcinomas. While it is accepted that Fascin-1 expression correlates with poor clinical outcome and decreased survival in various carcinomas, its role in sarcoma such as osteosarcoma (OS) remains un...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337773/ https://www.ncbi.nlm.nih.gov/pubmed/30654764 http://dx.doi.org/10.1186/s12885-019-5303-3 |