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Fascin-1 enhances experimental osteosarcoma tumor formation and metastasis and is related to poor patient outcome

BACKGROUND: Fascin-1, a prominent actin-bundling protein, is found to be upregulated in several human carcinomas. While it is accepted that Fascin-1 expression correlates with poor clinical outcome and decreased survival in various carcinomas, its role in sarcoma such as osteosarcoma (OS) remains un...

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Detalles Bibliográficos
Autores principales: Arlt, Matthias J., Kuzmanov, Aleksandar, Snedeker, Jess G., Fuchs, Bruno, Silvan, Unai, Sabile, Adam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337773/
https://www.ncbi.nlm.nih.gov/pubmed/30654764
http://dx.doi.org/10.1186/s12885-019-5303-3