Liver DNA methylation of FADS2 associates with FADS2 genotypex

BACKGROUND: Non-alcoholic fatty liver disease has been associated with increased mRNA expression of FADS2 in the liver and estimated activity of delta-6 desaturase in serum, encoded by the FADS2 gene. Since DNA methylation in the FADS1/2/3 gene cluster has been previously linked with genetic variant...

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Detalles Bibliográficos
Autores principales: Walle, Paula, Männistö, Ville, de Mello, Vanessa Derenji, Vaittinen, Maija, Perfilyev, Alexander, Hanhineva, Kati, Ling, Charlotte, Pihlajamäki, Jussi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337806/
https://www.ncbi.nlm.nih.gov/pubmed/30654845
http://dx.doi.org/10.1186/s13148-019-0609-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337806/
https://www.ncbi.nlm.nih.gov/pubmed/30654845
http://dx.doi.org/10.1186/s13148-019-0609-1

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