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Liver DNA methylation of FADS2 associates with FADS2 genotypex
BACKGROUND: Non-alcoholic fatty liver disease has been associated with increased mRNA expression of FADS2 in the liver and estimated activity of delta-6 desaturase in serum, encoded by the FADS2 gene. Since DNA methylation in the FADS1/2/3 gene cluster has been previously linked with genetic variant...
Autores principales: | Walle, Paula, Männistö, Ville, de Mello, Vanessa Derenji, Vaittinen, Maija, Perfilyev, Alexander, Hanhineva, Kati, Ling, Charlotte, Pihlajamäki, Jussi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337806/ https://www.ncbi.nlm.nih.gov/pubmed/30654845 http://dx.doi.org/10.1186/s13148-019-0609-1 |
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