Cargando…

Podoplanin (PDPN) affects the invasiveness of thyroid carcinoma cells by inducing ezrin, radixin and moesin (E/R/M) phosphorylation in association with matrix metalloproteinases

BACKGROUND: Podoplanin (PDPN) is a mucin-type transmembrane glycoprotein specific to the lymphatic system. PDPN expression has been found in various human tumors and is considered to be a marker of cancer. We had previously shown that PDPN expression contributes to carcinogenesis in the TPC1 papilla...

Descripción completa

Detalles Bibliográficos
Autores principales: Sikorska, Justyna, Gaweł, Damian, Domek, Hanna, Rudzińska, Magdalena, Czarnocka, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337816/
https://www.ncbi.nlm.nih.gov/pubmed/30654768
http://dx.doi.org/10.1186/s12885-018-5239-z