Cargando…

Podoplanin (PDPN) affects the invasiveness of thyroid carcinoma cells by inducing ezrin, radixin and moesin (E/R/M) phosphorylation in association with matrix metalloproteinases

BACKGROUND: Podoplanin (PDPN) is a mucin-type transmembrane glycoprotein specific to the lymphatic system. PDPN expression has been found in various human tumors and is considered to be a marker of cancer. We had previously shown that PDPN expression contributes to carcinogenesis in the TPC1 papilla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sikorska, Justyna, Gaweł, Damian, Domek, Hanna, Rudzińska, Magdalena, Czarnocka, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337816/ https://www.ncbi.nlm.nih.gov/pubmed/30654768 http://dx.doi.org/10.1186/s12885-018-5239-z

Ejemplares similares

Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin
por: Tachibana, Kouichi, et al.
Publicado: (2015)

Pharmacologic Inhibition of Ezrin-Radixin-Moesin Phosphorylation is a Novel Therapeutic Strategy in Rhabdomyosarcoma
por: Proudfit, Austin, et al.
Publicado: (2020)

The Role of Podoplanin in the Biology of Differentiated Thyroid Cancers
por: Rudzińska, Magdalena, et al.
Publicado: (2014)

Immunohistochemical analysis of ezrin-radixin-moesin-binding phosphoprotein 50 in prostatic adenocarcinoma
por: Bartholow, Tanner L, et al.
Publicado: (2011)

Ezrin/Radixin/Moesin Proteins and Flotillins Cooperate to Promote Uropod Formation in T Cells
por: Martinelli, Sibylla, et al.
Publicado: (2013)

CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation
por: Cannon, J. L., et al.
Publicado: (2011)

PKCθ Regulates T Cell Motility via Ezrin-Radixin-Moesin Localization to the Uropod
por: Cannon, Judy L., et al.
Publicado: (2013)

Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association
por: Matsui, Takeshi, et al.
Publicado: (1998)

ERM (Ezrin/Radixin/Moesin)-based Molecular Mechanism of Microvillar Breakdown at an Early Stage of Apoptosis
por: Kondo, Takahisa, et al.
Publicado: (1997)

In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin
por: Killock, David J., et al.
Publicado: (2009)

Two Sides of the Coin: Ezrin/Radixin/Moesin and Merlin Control Membrane Structure and Contact Inhibition
por: Michie, Katharine A., et al.
Publicado: (2019)

Elucidation of Short Linear Motif-Based Interactions of the FERM Domains of Ezrin, Radixin, Moesin, and Merlin
por: Ali, Muhammad, et al.
Publicado: (2023)

Identification of EBP50: A PDZ-containing Phosphoprotein that Associates with Members of the Ezrin-Radixin-Moesin Family
por: Reczek, David, et al.
Publicado: (1997)

MicroRNA-200b Impacts Breast Cancer Cell Migration and Invasion by Regulating Ezrin-Radixin-Moesin
por: Hong, Hong, et al.
Publicado: (2016)

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins
por: Riecken, Lars Björn, et al.
Publicado: (2016)

Ezrin-radixin-moesin proteins are regulated by Akt-GSK3β signaling in the rat nucleus accumbens core
por: Kim, Wha Young, et al.
Publicado: (2020)

Direct Involvement of Ezrin/Radixin/Moesin (ERM)-binding Membrane Proteins in the Organization of Microvilli in Collaboration with Activated ERM Proteins
por: Yonemura, Shigenobu, et al.
Publicado: (1999)

Cortical Mechanics and Meiosis II Completion in Mammalian Oocytes Are Mediated by Myosin-II and Ezrin-Radixin-Moesin (ERM) Proteins
por: Larson, Stephanie M., et al.
Publicado: (2010)

Ubiquitination within the membrane-proximal ezrin-radixin-moesin (ERM)-binding region of the L1 cell adhesion molecule
por: Aikawa, Yoshikatsu
Publicado: (2013)

Immunohistochemical staining of radixin and moesin in prostatic adenocarcinoma
por: Bartholow, Tanner L, et al.
Publicado: (2011)

The role of prospero homeobox 1 (PROX1) expression in follicular thyroid carcinoma cells
por: Rudzinska, Magdalena, et al.
Publicado: (2017)

Rho- and Rac-dependent Assembly of Focal Adhesion Complexes and Actin Filaments in Permeabilized Fibroblasts: An Essential Role for Ezrin/Radixin/Moesin Proteins
por: Mackay, Deborah J.G., et al.
Publicado: (1997)

ICAM-2 regulates vascular permeability and N-cadherin localization through ezrin-radixin-moesin (ERM) proteins and Rac-1 signalling
por: Amsellem, Valerie, et al.
Publicado: (2014)

Role of Ezrin/Radixin/Moesin in the Surface Localization of Programmed Cell Death Ligand-1 in Human Colon Adenocarcinoma LS180 Cells
por: Kobori, Takuro, et al.
Publicado: (2021)

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway
Publicado: (1996)

Temporal and Spatial Regulation of Ezrin-Radixin-Moesin-Binding Phosphoprotein-50-kDa (EBP50) during Embryo Implantation in Mouse Uterus
por: Li, Xing, et al.
Publicado: (2012)

Perspectives for Ezrin and Radixin in Astrocytes: Kinases, Functions and Pathology
por: Derouiche, Amin, et al.
Publicado: (2019)

Identification of Ezrin-Radixin-Moesin proteins as novel regulators of pathogenic B cell receptor signaling and tumor growth in diffuse large B cell lymphoma
por: Pore, Debasis, et al.
Publicado: (2015)

Ezrin–Radixin–Moesin Binding Phosphoprotein 50: A Potential Novel Biomarker in Human Papilloma Virus-Associated Head and Neck Squamous Cell Carcinomas
por: Shankar, Athiva, et al.
Publicado: (2018)

Subcellular distribution of ezrin/radixin/moesin and their roles in the cell surface localization and transport function of P-glycoprotein in human colon adenocarcinoma LS180 cells
por: Kobori, Takuro, et al.
Publicado: (2021)

The role of the transcription factor - Prospero homeobox 1 (Prox1) in the biology of differentiated thyroid cancer - the effect of the expression of Prox1 on migration and invasiveness of thyroid cancer cells
por: Rudzińska, Magdalena, et al.
Publicado: (2013)

Contribution of radixin and ezrin to the maintenance of hepatocytes' excretory function in health and disease
por: Dellbrügge, Friederike, et al.
Publicado: (2023)

Are Podoplanin and Ezrin Involved in the Invasion Process of the Ameloblastomas?
por: Costa, Y.F., et al.
Publicado: (2015)

Ezrin/Radixin/Moesin (ERM) Proteins Bind to a Positively Charged Amino Acid Cluster in the Juxta-Membrane Cytoplasmic Domain of CD44, CD43, and ICAM-2
por: Yonemura, Shigenobu, et al.
Publicado: (1998)

The activation of ezrin–radixin–moesin proteins is regulated by netrin-1 through Src kinase and RhoA/Rho kinase activities and mediates netrin-1–induced axon outgrowth
por: Antoine-Bertrand, Judith, et al.
Publicado: (2011)

Telencephalin protects PAJU cells from amyloid beta protein-induced apoptosis by activating the ezrin/radixin/moesin protein family/phosphatidylinositol-3-kinase/protein kinase B pathway☆
por: Yang, Heping, et al.
Publicado: (2012)

Resolving the role of podoplanin in the motility of papillary thyroid carcinoma-derived cells using RNA sequencing
por: Mielecki, Damian, et al.
Publicado: (2023)

Ezrin and Moesin Are Required for Efficient T Cell Adhesion and Homing to Lymphoid Organs
por: Chen, Emily J. H., et al.
Publicado: (2013)

Suppression of Radixin and Moesin Alters Growth Cone Morphology, Motility, and Process Formation In Primary Cultured Neurons
por: Paglini, Gabriela, et al.
Publicado: (1998)

The relationship between ezrin and podoplanin expressions in keratocystic odontogenic tumors
por: Oliveira, Denise Tostes, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_769om2p433ggukob51utf2q9ik