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The evolution of transcriptional repressors in the Notch signaling pathway: a computational analysis
BACKGROUND: The Notch signaling pathway governs the specification of different cell types in flies, nematodes and vertebrates alike. Principal components of the pathway that activate Notch target genes are highly conserved throughout the animal kingdom. Despite the impact on development and disease,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337844/ https://www.ncbi.nlm.nih.gov/pubmed/30679936 http://dx.doi.org/10.1186/s41065-019-0081-0 |