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Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)

INTRODUCTION: Clinical studies suggest that obesity, in addition to promoting breast cancer aggressiveness, is associated with a decrease in chemotherapy efficacy, although the mechanisms involved remain elusive. As chemotherapy is one of the main treatments for aggressive or metastatic breast cance...

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Detalles Bibliográficos
Autores principales: Lehuédé, Camille, Li, Xia, Dauvillier, Stéphanie, Vaysse, Charlotte, Franchet, Camille, Clement, Emily, Esteve, David, Longué, Mélanie, Chaltiel, Léonor, Le Gonidec, Sophie, Lazar, Ikrame, Geneste, Aline, Dumontet, Charles, Valet, Philippe, Nieto, Laurence, Fallone, Frédérique, Muller, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337862/
https://www.ncbi.nlm.nih.gov/pubmed/30654824
http://dx.doi.org/10.1186/s13058-018-1088-6