Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation

BACKGROUND: Parkinson’s disease (PD) is characterized by a chronic loss of dopaminergic neurons and the presence of proteinaceous inclusions (Lewy bodies) within some remaining neurons in the substantia nigra. Recently, astroglial inclusion body has also been found in some neurodegenerative diseases...

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Detalles Bibliográficos
Autores principales: Lu, Shen-zhao, Guo, Yong-shun, Liang, Pei-zhou, Zhang, Shu-zhen, Yin, Shu, Yin, Yan-qing, Wang, Xiao-min, Ding, Fei, Gu, Xiao-song, Zhou, Jia-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337871/
https://www.ncbi.nlm.nih.gov/pubmed/30675347
http://dx.doi.org/10.1186/s40035-018-0143-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337871/
https://www.ncbi.nlm.nih.gov/pubmed/30675347
http://dx.doi.org/10.1186/s40035-018-0143-7

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