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In vitro reconstitution of DNA replication initiated by genetic recombination: a T4 bacteriophage model for a type of DNA synthesis important for all cells

Using a mixture of 10 purified DNA replication and DNA recombination proteins encoded by the bacteriophage T4 genome, plus two homologous DNA molecules, we have reconstituted the genetic recombination–initiated pathway that initiates DNA replication forks at late times of T4 bacteriophage infection....

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Detalles Bibliográficos
Autores principales: Barry, Jack, Wong,, Mei Lie, Alberts, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337909/
https://www.ncbi.nlm.nih.gov/pubmed/30403545
http://dx.doi.org/10.1091/mbc.E18-06-0386